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Some conditions that are associated with a lower fetal exposure to 3-THP and other neuroactive steroids are high exposure to maternal stress, increased cortisol levels, or preterm birth (204)

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In addition to its effects on insulin, GIP plays a crucial role in fat accumulation by promoting the activity of adipocyte-expressed lipoprotein lipase and promoting bone formation by preventing osteoclast apoptosis, as evidenced by the thinner bone trabeculae seen in mice lacking GIP receptors [20,21,22]